Safety and Side Effects

is raspberry ketone safeWe like to think of "natural" supplements like raspberry ketone as not containing any chemicals. However everything in nature is made of chemicals - just naturally-occurring ones instead of those which have been manufactured in the lab. These natural substances in raspberry ketones are what make it effective, but they may also have adverse effects upon certain people. While RK is considered to be safe for most healthy adults when taken at the recommended dosage, it does have a few characteristics you should be aware of.

Stimulant Properties

Raspberry Ketone contains a compound which stimulates the sympathetic nervous system and increases the release of the hormone and neurotransmitter norepinephrine. This increases your metabolic rate and improves concentration, but can also cause:

  • increased blood pressure
  • increased heart rate - palpitations have occasionally been reported, according to WebMD
  • jitteriness and anxiety
  • trouble sleeping

In the research study conducted on humans, no significant changes in heart rate or blood pressure occurred in healthy adults. A few experienced mild, temporary stomach upset .

Raspberry ketones may not be a good choice for people with certain medical conditions including;

  • Diabetes - RK contains a chemical adiponectin, which has been shown to lower blood glucose, however the release of norepinephrine may actually elevate it. These two opposite reactions could cause unpredictable fluctuations in your blood glucose and make your condition more difficult to manage.
  • High Blood Pressure or cardiovascular disease
  • Asthma or COPD
  • IBD/IBS - (Inflammatory bowel disease or irritable bowel syndrome) or Chron's disease.
  • Anxiety
  • People who are taking antidepressants or anti-anxiety medications

If you are in one of these groups or have other health concerns, please ask your doctor if raspberry ketone is right for you.


clinical studiesSubstances which are anti-androgenic suppress the hormone androgen. Lots of foods and herbal medicines, including capsaicin (red pepper) have this property - taken in moderation, it's not normally a concern. Some people take anti-androgenic prescription drugs to treat conditions including acne and prostate disease.

If you are currently on an anti-androgenic medication or have a family history of estrogen-related disease or a medical condition which can be triggered by estrogen (such as certain types of cancer), please seek the advice of your physician before taking this supplement.

Groups in which raspberry ketone is untested

Like most diet supplements, Raspberry ketone has not been tested on women who are pregnant or nursing, or on children and teens under age 18. If you are in one of these categories, it is highly recommended that you speak with a trusted physician before starting on a raspberry ketone diet.

Mega-doses of this supplement have also not been tested on human subjects.

Allergy concerns

Since this supplement is a derivative of raspberries, it should be avoided if you have a known allergy to raspberries, blackberries or related plants.


The FDA (US Food and Drug Administration) has not issued any statements on the safety of RK as a diet supplement. However, in the small quantities in which it is used as a food additive, raspberry ketone has been on the FDA's GRAS ("generally recognized as safe") list since 1965.

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